Stem cell therapy
Stem cells are basically plain cells that can become brain cells, skin cells, heart cells, liver cells, or any other type of cells for that matter. And their potential use in regenerative medicine is enormous.
When being taken out of the cord blood after the childbirth, stem cells are usually collected and safely preserved in order to treat various medical conditions, if those occur later on throughout the child’s lifetime.
Those are traditionally embryonic stem cells, often derived from embryos in a pre-embryonic phase, so there might not be a guarantee that those would be capable of producing stem cell lines that match the patient.
But then, in the early 2000’s Japanese scientist Shinya Yamanaka pioneered a new technology in his Kyoto lab. It was the moment of the invention of induced pluripotent stem cells (iPSCs). Along with Sir John Gordon, Yamanaka showed that four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells. They were awarded the Nobel Prize in 2012 for their discovery.
Why are their findings so important? And how have the stem cell medicine evolved ever since? What are the latest innovations in this field?
We provide you some of the answers here.
NIH National Institute of Health about stem cells.
Proved Efficiency in Treating Various Conditions
Since the discovery that pluripotent stem cells can be derived directly from adult tissue, there is no more such a strong need for embryonic stem cells which may or may not match the patient. After various scientific studies, research projects, and clinical trials in some of the most prominent medical centers around the world, it has been proven that stem cells can be effective in treating different kinds of diseases or injuries.
Studies have shown that stem cells may be used to prevent or treat conditions such as:
- Alzheimer’s disease
- Parkinson’s disease
- Hodgkin’s lymphoma
- Heart disease
- Type 1 Diabetes
- Multiple Sclerosis
- Spinal cord injury
- Muscular dystrophy
- Repairing damaged tissue
- Bone regeneration
Since they are genetically engineered, pluripotent stem cells can be made to match the patient and, therefore, to create a unique stem cell line for every individual. They could potentially be used to generate transplants without a risk of an immune rejection, but that hasn’t been claimed safe enough yet.
Top 5 latest stem cell innovations
Advances in the field of stem cell therapy include the newest developments in genetic technologies, cellular and alternative therapies, sequencing technologies, and genetically altered animals.
Here follow some of the most significant innovations.
1.A new way of helping diabetes patients
Researchers at Washington University School of Medicine in St. Louis and Harvard University managed to take stem cells derived from the skin of diabetes patients and convert them into the insulin-secreting cells. This new treatment is still in its research phase, but if proved to be fully effective, it could vastly help patients with Type 1 diabetes and change the way they take insulin medications.
2.Injectable 3D Cell Delivery Matrix
Matrices used for cell delivery provide support to transplanted cells, and the innovative non-invasive injectable matrices appear to be essential for promoting cell survival and desirable phenotypes.
3.Nanohydrogel For Muscular Dystrophy
A new nanohydrogel with muscle stem cells was successfully tested in the lab at Georgia Insititute of Technology. It brought a big muscle growth to lab mice while protecting the cells from immune reactions which could potentially annihilate them. Researchers agree that elderly and muscular dystrophy patients could vastly benefit from this nanohydrogel in the future.
4.Ultra-High Bioelectric Stem Cells Signal
Researchers at the Singapore University of Technology and Design have found a way to produce highest-ever signals for human embryonic stem cell detection. They used direct current-voltage methods and few-layered 2D molybdenum disulphide sheets, and they managed to achieve cell signals that were two-orders of magnitude higher than previous electrical-based detections. It could be of the utmost significance for developing a damage-free method for identifying stem cell pluripotency.
5.3D Bioprinting with Chemical Sensors
Experts from the Faculty of Science at the University of Copenhagen have found a new method of non-invasive monitoring of oxygen metabolism in cells that are 3D bioprinted into complex living structures. This discovery might have a big impact on the future design of 3D printed constructs, as it might advance an oxygen supply for stem cells throughout the bone and tissue reconstruction process.
The newest bioengineering technologies make possible for stem cells to generate indefinitely. Therefore, they are often seen as an unlimited source of autologous cells that can be used to replace damaged cells in the patient’s body. If you are dealing with a condition that can be treated with stem cells and you want the advanced treatment, you can use the Medical Tourism Directory to search for the best stem cell therapy clinics in the world, and get the best possible innovative medical care for you or your family members.
India is one of the countries with strongly developed system for treating various conditions using stem cells. The cost of stem cell therapy in India is on the ower side and the best stem cell treatment in India may be found in hospitals such as Sri Ramachandra University Hospital in Chinnai, or Indraprastha apollo Hospitals in New Delhi.
STEM CELL THERAPY CONDITIONS
- Alzheimer’s; Euro stem cell on Alzheimer’s and stem cells; Alzheimer’s society consultations.
- Anti aging; Swiss medica on anti aging stem cell treatment;
- Alsears MD on stem cell therapy.
- Arthritis; Arthritis research UK on osteoarthritis; Stem cell institute on stem cell therapy.
- Autism; Stem cell institute on stem cell therapy for autism; CIRM on autism stories of hope; UK San Diego School of medicine on stem cell studies from the Autism center.
- Foundation; National Stem Cell Foundation.
- Cerebral Palsy; Euro stem cell on cerebral palsy; Cerebral palsy guide on a cure for cerebral palsy.
- COPD (Chronic Obstructive Pulmonary Disease); Lung institute on stem cell treatment; Lung stem cells in health, repair and disease.
- Diabetes; Diabetes research institute on turning stem cells into insulin-producing cells;
- Hemiplegia; https://chaitanyastemcell.co.in/mobile/Stroke_Hemiplegia.aspx.
- Heart Disease; A closer look on stem cells on heart disease.
- Hodgkin’s lymphoma; Cancer network on lymphoma; Lymphoma Australia on bone marrow and stem-cell transplantation.
- Leukemia; Cancer treatment centers of America on leukemia stem cell transplantation; Euro stem cell on leukemia and stem cells.
- SLE Systemic lupus erythematosus; Lupus foundation on stem cells research and lupus.
- MS Multiple sclerosis.
- Multiple myeloma.
- Non-Hodgkin lymphoma; Cancer network on lymphoma; Lymphoma Australia on bone marrow and stem-cell transplants.
- Parkinson’s disease; Euro stem cell on parkinson’s disease and stem cells;
- Stroke; Stroke association on brain damage caused by stroke; Stem cells and stroke.
- Sickle cell disease; NHS on stem cell transplant reverses sickle Cell disease in adults; NIH on stem cell transplant reverses sickle cell disease in adults.
- Thalassemia; NHS on thalassemia treatments.
STEM CELL THERAPY TREATMENTS
- Bone regeneration.
- Cartilage regeneration.
- Stem cell transplants.